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One-molar gadolinium chelate (gadobutrol) as a contrast agent for CT angiography of the thoracic and abdominal aorta

✍ Scribed by José M. Esteban; Antonio Alonso; Vicente Cervera; Vicente Martínez


Book ID
113031413
Publisher
Springer
Year
2007
Tongue
English
Weight
212 KB
Volume
17
Category
Article
ISSN
0938-7994

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The introduction of a lipophilic moiety into the gadolinium chelate Gd-DTPA (dimeglumine gadopentetate, Magnevist) yielded Gd-EOB-DTPA (short form), which has potential as a magnetic resonance contrast agent for liver mass screening. The pharmacokinetics of Gd-EOB-DTPA in rats is nonlinear because a