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Use of a Dipeptide Chemical Library in the Development of Non-Peptide Tachykinin NK 3 Receptor Selective Antagonists

✍ Scribed by Boden, Phil; Eden, Jon M.; Hodgson, Julie; Horwell, David C.; Hughes, John; McKnight, Alexander T.; Lewthwaite, Russell A.; Pritchard, Martyn C.; Raphy, Jenny; Meecham, Ken; Ratcliffe, Giles S.; Suman-Chauhan, Nirmala; Woodruff, Geoffrey N.


Book ID
127307800
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
413 KB
Volume
39
Category
Article
ISSN
0022-2623

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πŸ“œ SIMILAR VOLUMES


The development of a novel series of non
✍ P. Boden; J.M. Eden; J. Hodgson; D.C. Horwell; M.C. Pritchard; J. Raphy; N. Suma πŸ“‚ Article πŸ“… 1995 πŸ› Elsevier Science 🌐 English βš– 222 KB

In this paper we describe the transformation of a series of modified dipeptide NK 3 receptor selective ligands, previously developed from a hit identified from the screening of a dipeptide chemical library, into non-peptide, nanomolar affinity NK 3 receptor selective antagonists eg. PD160946 and PD1