✦ LIBER ✦

Use and detection of nonradioactive lodine-labeled antibodies for immunoassay

✍ Scribed by Richard O'Kennedy; Paula Keating

Publisher: Elsevier Science
Year: 1991
Tongue: English
Weight: 396 KB
Volume: 194
Category: Article
ISSN: 0003-2697
DOI: 10.1016/0003-2697(91)90238-o

No coin nor oath required. For personal study only.

✦ Synopsis

Traditionally radioactively labeled iodine has been used as a reporter group for the detection of antibodies in immunoassay. We have recently developed a microassay system for the detection of very low concentrations of iodide which eliminates the need for the use of radiolabeled iodine (O'Kennedy, R. et al. 1989, Anal. Biochem. 179, 138-144). The successful application of this assay for the detection of mouse IgG is described. The performance of this system compared with enzyme immunoassay was evaluated.

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