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Ursodeoxycholic acid (UDCA) for symptomatic primary biliary cirrhosis (PBC): A double-blind multicenter trial

Book ID
122776931
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
73 KB
Volume
9
Category
Article
ISSN
0168-8278

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๐Ÿ“œ SIMILAR VOLUMES

The canadian multicenter double-blind ra
The canadian multicenter double-blind randomized controlled trial of ursodeoxycholic acid in primary biliary cirrhosis
โœ E. Jenny Heathcote; Karen Cauch-Dudek; Valery Walker; Robert J. Bailey; Laurence ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 969 KB

Ursodeoxycholic acid, a dihydroxyl bile acid normally present in human beings in minimal amounts, becomes incorporated into the bile salt pool when taken orally. In cholestasis, bile acids are retained in the liver and are hepatotoxic. Ursodeoxycholic acid is the least-known hepatotoxic bile acid, h

A randomized, double-blind, placebo-cont
A randomized, double-blind, placebo-controlled trial of ursodeoxycholic acid in primary biliary cirrhosis
โœ Burton Combes; Robert L. Carithers Jr.; Willis C. Maddrey; Danyu Lin; Dr Mary F. ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 792 KB

One hundred fifty-one patients with primary biliary cirrhosis (PBC) grouped into four strata based on entry serum bilirubin (<2 mg/dL vs. 2 mg/dL or greater) and liver histology (stages I, 1 1 vs. stages 111, IV-Ludwig criteria) were randomized within each stratum to ursodiol or placebo given in a s