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Ursodeoxycholic acid in cholestasis: linking action mechanisms to therapeutic applications

✍ Scribed by Roma, Marcelo G.; Toledo, Flavia D.; Boaglio, Andrea C.; Basiglio, Cecilia L.; Crocenzi, Fernando A.; Sánchez Pozzi, Enrique J.

Book ID
117990813
Publisher
Portland Press
Year
2011
Tongue
English
Weight
528 KB
Volume
121
Category
Article
ISSN
0143-5221

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✦ Synopsis

Aging is a biological process that affects most cells, organisms and species. Human aging is associated with increased susceptibility to a variety of chronic diseases, including cardiovascular disease, Type 2 diabetes, neurological diseases and cancer. Despite the remarkable progress made during the last two decades, our understanding of the biology of aging remains incomplete. Telomere biology has recently emerged as an important player in the aging and disease process.

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Ursodeoxycholic acid in cholestasis: Pot
Ursodeoxycholic acid in cholestasis: Potential mechanisms of action and therapeutic applications
✍ Ulrich Beuers; James L. Boyer; Gustav Paumgartner 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 74 KB

The dihydroxy bile acid, ursodeoxycholic acid (UDCA), is increasingly used for the treatment of chronic cholestatic liver diseases. First reports of a beneficial effect on serum liver tests in cholestatic disorders were published in the 1980s in the Western literature, 1-3 but similar observations h