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Urokinase-type plasminogen activator up-regulates the expression of its cellular receptor through a post-transcriptional mechanism

โœ Scribed by Nunzia Montuori; Amalia Mattiello; Alessandro Mancini; Mariano Santoli; Paola Taglialatela; Mario Caputi; Guido Rossi; Pia Ragno

Book ID
117103622
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
288 KB
Volume
508
Category
Article
ISSN
0014-5793

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The urokinase-type plasminogen activator (uPA) and its receptor (uPAR) play an important role in tumour invasion. Previous studies have shown by RT-PCR that uPA and uPAR mRNAs are expressed in human hepatocellular carcinoma (HCC). Here, in situ hybridization, immunohistochemistry, and double immunoยฏ