## Background: Telomerase is an enzyme that can reconstitute the ends (telomeres) of chromosomes after cell division and thus circumvent the cumulative damage that occurs in normal adult somatic cells during successive mitotic cycles. recently, it has been proposed that this enzyme should, therefor
Urine telomerase for diagnosis of bladder cancer
β Scribed by Roxanne Nelson
- Book ID
- 117783732
- Publisher
- The Lancet
- Year
- 2005
- Tongue
- English
- Weight
- 73 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1470-2045
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Early diagnosis is still the most important prerequisite for successful cancer treatment and this holds true for bladder cancer. Urine cytology is commonly used as a non-invasive screening procedure for the detection of bladder carcinoma, but this method is labour-intensive and often generates false
## Abstract The aim of our study was to prospectively evaluate the potential diagnostic value and clinical applicability of quantitative analysis of telomerase subunits gene expression in urine for noninvasive detection of bladder cancer. Expression levels of human telomerase reverse transcriptase