Human chorionic gonadotropin (hCG) free beta-subunit levels were determined in 709 control and 13 Down syndrome urine samples from the second trimester of pregnancy. Results were normalized to urine creatinine concentration and converted to multiples of the unaffected pregnancy medium (MOM). The con
Urine free beta-hCG and total estriol for Down syndrome screening during the second trimester in an Asian population
✍ Scribed by Jenn J Hsu; Te Y Hsu; T’Sang T Hsieh; Yung K Soong; Fon J Hsieh; Kevin Spencer
- Book ID
- 117193315
- Publisher
- Lippincott Williams and Wilkins
- Year
- 1999
- Tongue
- English
- Weight
- 178 KB
- Volume
- 94
- Category
- Article
- ISSN
- 0029-7844
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We have examined maternal urine concentrations of beta core, free beta human chorionic gonadotrophin (hCG), and total oestriol in 373 control pregnancies and 43 pregnancies affected by aneuploidy (including 22 cases of Down's syndrome) in an attempt to see if any of the analytes have a value in Down
In a study of 69 random urine samples from cases of Down syndrome and 405 samples from unaffected pregnancies, we have assessed the value of various candidate markers that have been proposed as tools for screening for Down syndrome. We found that the marker urine free beta hCG in Down syndrome had a