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Urine analysis by laser Raman spectroscopy

✍ Scribed by W. Ranjith Premasiri; Richard H. Clarke; M. Edward Womble

Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
179 KB
Volume
28
Category
Article
ISSN
0196-8092

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✦ Synopsis

Abstract

Background and Objective

We examine the use of Raman spectroscopy to analyze components in human urine.

Study Design/Materials and Methods

Targeted urine components include urea, uric acid, and creatinine.

Results

Urea concentration in urine is sufficiently high that normal Raman spectroscopy may be used for its analysis. All other components are in low concentrations requiring the use of surface‐enhanced Raman spectroscopic methods (SERS).

Conclusions

Both normal Raman and SERS approaches have been investigated for total urine‐nitrogen determination, urine urea‐nitrogen determination, and for the urea/creatinine excretion ratio. Lasers Surg. Med. 28:330–334, 2001. Β© 2001 Wiley‐Liss, Inc.

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