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Urinary Metabolites from F344 Rats and B6C3F1 Mice Coadministered Acrylamide and Acrylonitrile for 1 or 5 Days

โœ Scribed by Sumner, Susan C. J.; Selvaraj, Leena; Nauhaus, Sara K.; Fennell, Timothy R.

Book ID
126818926
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
163 KB
Volume
10
Category
Article
ISSN
0893-228X

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Glycidol, a simple aliphatic epoxide, was administered by gavage in water to groups of male and female F344/N rats and B6C3F1 mice. Rats received 0, 37.5 or 75 mg kg-' and mice received 0, 25 or 50 mg kg-' daily, 5 days per week for 2 years. Exposure to glycidol was associated with dose-related incr