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Urinary matrix metalloproteinase-7 level is associated with the presence of metastasis in bladder cancer

✍ Scribed by Tibor Szarvas; Bernhard B. Singer; Markus Becker; Frank vom Dorp; Tobias Jäger; Attila Szendrői; Péter Riesz; Imre Romics; Herbert Rübben; Süleyman Ergün

Book ID: 110923142
Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 279 KB
Volume: 107
Category: Article
ISSN: 1464-4096
DOI: 10.1111/j.1464-410x.2010.09625.x

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## Abstract Matrix metalloproteinases (MMPs) play an important role in several steps of cancer development. A single guanine insertion polymorphism (2G) in the __MMP1__ promoter sequence at −1,607 creates an Ets binding site and thus results in enhancing transcriptional activity. This study aimed t