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Urinary excretion of phenobarbital and its metabolitep-hydroxyphenobarbital in convulsing and non-convulsing patients

✍ Scribed by B. Brzakovic; M. Pokrajac; E. Dzoljic; Z. Levic; V. M. Varagic

Publisher
Springer-Verlag
Year
1999
Tongue
English
Weight
407 KB
Volume
24
Category
Article
ISSN
0378-7966

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πŸ“œ SIMILAR VOLUMES

Urinary excretion of phenobarbitone and
Urinary excretion of phenobarbitone and its metabolites in chronically treated patients
✍ I. Bernus; R. G. Dickinson; W. D. Hooper; M. J. Eadie πŸ“‚ Article πŸ“… 1994 πŸ› Springer 🌐 English βš– 305 KB

The elimination of phenobarbitone (PB) was studied in 14 chronically treated epileptic patients under steady state conditions. PB, [S]-PB-N-glucoside ( [S]-PB-N-G) and p-hydroxy-PB (p-OH-PB) were assayed in urine by a HPLC method. Some 57 % of the daily dose was recovered in urine, 14 % as [S]-PB-N