𝔖 Bobbio Scriptorium
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Urinary excretion of acrylonitrile and its metabolites in rats

✍ Scribed by G. Müller; C. Verkoyen; N. Soton; K. Norpoth


Publisher
Springer-Verlag
Year
1987
Tongue
English
Weight
286 KB
Volume
60
Category
Article
ISSN
0340-5761

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✍ I. Bernus; R. G. Dickinson; W. D. Hooper; M. J. Eadie 📂 Article 📅 1994 🏛 Springer 🌐 English ⚖ 305 KB

The elimination of phenobarbitone (PB) was studied in 14 chronically treated epileptic patients under steady state conditions. PB, [S]-PB-N-glucoside ( [S]-PB-N-G) and p-hydroxy-PB (p-OH-PB) were assayed in urine by a HPLC method. Some 57 % of the daily dose was recovered in urine, 14 % as [S]-PB-N