A simple and sensitive high-performance liquid chromatography method with electrochemical detector is described for the determination of free 3-methoxy-4-hydroxyphenylacetic acid (HVA) in human plasma. The method does not involve any extraction, is specific and reproducible, and has the potential to
Urinary excretion of 3-methoxy-4-hydroxymandelic acid in children with neuroblastoma
✍ Scribed by Stella B. Kontras
- Publisher
- John Wiley and Sons
- Year
- 1962
- Tongue
- English
- Weight
- 766 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0008-543X
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✦ Synopsis
R3ISTKONG and co-workers2 in 1956 first de-A scribed a metabolite of norepinephrine in human urine that Armstrong et al.3 in 1957 idcntified a5 3-r1iethoxy-4-Lrvdroxyluandelic acid, or vanilmandelic acid (VMA). 'This phenolic ;Icid was soon confirmed to be the chief bie;iktlown product of norepinephrine and epinephrine and represents a measure of ca-__ &'ioin I Irc tlepnrtnicnts of Pediatrics antl Pathology, Cliildrcn's Hospital,
📜 SIMILAR VOLUMES
## Abstract 3‐Acetyltropolone (1) reacted with benzaldehydes in trimethyl orthoformate in the presence of perchloric acid to afford 2‐aryl‐4‐methoxy‐9‐oxocyclohepta[__b__]pyrylium perchlorates 3a‐c in 25–37% yields. From the filtrates, 3‐(3,4‐diaryl‐3‐butenoyl)tropolones 4a,b and 3‐(2‐methoxycinnam