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Uridine Diphosphate Glucuronosyltransferase (UGT) 1A1 and Irinotecan: Practical Pharmacogenomics Arrives in Cancer Therapy

✍ Scribed by O'Dwyer, P. J.


Book ID
111910971
Publisher
American Society of Clinical Oncology
Year
2006
Tongue
English
Weight
82 KB
Volume
24
Category
Article
ISSN
0732-183X

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✍ Heather Taffet Gold; Michael J. Hall; Victoria Blinder; Bruce R. Schackman πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 201 KB

## Abstract ## BACKGROUND: The objective of this study was to examine the cost effectiveness of using a pharmacogenetic test for uridine diphosphate glycosyltransferase 1A1\*28 (UGT1A1\*28) variant homozygosity before administering irinotecan to patients with metastatic colorectal cancer. ## METH