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Ureido-Based Peptidomimetic Inhibitors of Herpes Simplex Virus Ribonucleotide Reductase: An Investigation of Inhibitor Bioactive Conformation

✍ Scribed by Moss, Neil; Beaulieu, Pierre; Duceppe, Jean-Simon; Ferland, Jean-Marie; Gauthier, Jean; Ghiro, Elise; Goulet, Sylvie; Guse, Ingrid; Llinàs-Brunet, Montse; Plante, Raymond

Book ID
115485333
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
454 KB
Volume
39
Category
Article
ISSN
0022-2623

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Peptidomimetic inhibitors of herpes viru
Peptidomimetic inhibitors of herpes virus ribonucleotide reductase. Correlation between herpes simplex and varicella zoster virus
✍ Montse Llinàs-Brunet; Neil Moss; Erika Scouten; Michel Liuzzi; Robert Déziel 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 259 KB

Peptidomimetic inhibitors based on the C-terminal sequence of herpes simplex virus (HSV) ribonucleotide reductase (RR) small subunit (R2) also inhibit varicella zoster virus (VZV) RR. There is generally good correlation between the potencies against both HSV and VZV RR. There are, however, two impor