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Peptidomimetic Inhibitors of Herpes Simplex Virus Ribonucleotide Reductase with Improved in Vivo Antiviral Activity

✍ Scribed by Moss, Neil; Beaulieu, Pierre; Duceppe, Jean-Simon; Ferland, Jean-Marie; Garneau, Michel; Gauthier, Jean; Ghiro, Elise; Goulet, Sylvie; Guse, Ingrid; Jaramillo, Jorge; Llinas-Brunet, Montse; Malenfant, Éric; Plante, Raymond; Poirier, Martin; Soucy, Francois; Wernic, Dominik; Yoakim, Christiane; Déziel, Robert

Book ID
127157427
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
452 KB
Volume
39
Category
Article
ISSN
0022-2623

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Peptidomimetic inhibitors of herpes viru
Peptidomimetic inhibitors of herpes virus ribonucleotide reductase. Correlation between herpes simplex and varicella zoster virus
✍ Montse Llinàs-Brunet; Neil Moss; Erika Scouten; Michel Liuzzi; Robert Déziel 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 259 KB

Peptidomimetic inhibitors based on the C-terminal sequence of herpes simplex virus (HSV) ribonucleotide reductase (RR) small subunit (R2) also inhibit varicella zoster virus (VZV) RR. There is generally good correlation between the potencies against both HSV and VZV RR. There are, however, two impor