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Uptake of Adriamycin in tumour and surrounding brain tissue in patients with malignant gliomas

✍ Scribed by H. von Holst; E. Knochenhauer; H. Blomgren; V. P. Collins; L. Ehn; M. Lindquist; G. Norén; C. Peterson

Publisher
Springer Vienna
Year
1990
Tongue
English
Weight
301 KB
Volume
104
Category
Article
ISSN
0001-6268

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Twenty patients with solid tumors received 30 mg/M2 of adriamycin. Various tissue samples were intraoperatively obtained from 18 patients, about 1.5-5 hours after an intravenous (IV) bolus dose. Normal liver showed the highest levels of adriamycin uptake (2.3-19.8 &g); lymph nodes were second; muscl