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Uptake by rat liver and intracellular fate of plasmid DNA complexed with poly-l-lysine or poly-d-lysine

✍ Scribed by Nathanael Laurent; Simone Wattiaux-De Coninck; Eugenie Mihaylova; Ekaterina Leontieva; Marie-Thérèse Warnier-Pirotte; Robert Wattiaux; Michel Jadot


Book ID
117110277
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
244 KB
Volume
443
Category
Article
ISSN
0014-5793

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## Abstract ## Background The efficient nuclear delivery of plasmid DNA (pDNA) is essential for the development of a promising non‐viral gene vector. In an attempt to achieve nuclear delivery, NLS‐mu, a novel pDNA condenser, was prepared. This consists of mu, a highly potent polypeptide for conden