Uptake and presentation of malignant glioma tumor cell lysates by monocyte-derived dendritic cells
✍ Scribed by Steven De Vleeschouwer; Mohammed Arredouani; Martine Adé; Pascal Cadot; Elke Vermassen; Jan. L. Ceuppens; Stefaan W. Van Gool
- Publisher
- Springer-Verlag
- Year
- 2004
- Tongue
- English
- Weight
- 524 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0340-7004
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Leukemic-dendritic cells (leukemic-DCs) have certain limitations, which include difficult generation in 30-40% of patients, and low levels of expression of several key molecules. Therefore, an alternative approach using monocyte-derived DCs pulsed with tumor antigens is required. We investigated the