## Abstract The Cdk9/Cyclin T1 complex is very important in controlling specific differentiative pathways of several cell types, including muscle cells and neurons. We recently demonstrated the involvement of this complex in B cell activation/differentiation. To check whether the Cdk9/Cyclin T1 com
Upregulation of cyclin T1/CDK9 complexes during T cell activation
✍ Scribed by Garriga, Judit; Peng, Junmin; Parreño, Matilde; Price, David H; Henderson, Earl E; Graña, Xavier
- Book ID
- 110061992
- Publisher
- Nature Publishing Group
- Year
- 1998
- Tongue
- English
- Weight
- 445 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0950-9232
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## Abstract Cdk9/Cyclin T1 complex is very important in controlling specific differentiative pathways of several cell types. Limited data are available regarding the expression of Cdk9/Cyclin T1 in hematopoietic and lymphoid tissues. Cdk9/Cyclin T1 expression seems to be related to particular stage
## Abstract Cdk9 and its binding partner cyclin T1 comprise the positive elongation factor b (P‐TEFb). P‐TEFb phosphorylates the RNA polymerase II carboxyl‐terminal‐domain (CTD) allowing efficient transcription elongation. Recent studies showed that Cdk9 is a predominant nuclear protein, and here w