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Upregulation and dephosphorylation of cofilin: Modulation by CD44 variant isoform in human colon cancer cells

โœ Scribed by Venkateswaran Subramaniam; Isabella R. Vincent; Serge Jothy

Book ID
113956403
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
290 KB
Volume
79
Category
Article
ISSN
0014-4800

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CD44 is a glycosylated adhesion molecule which may undergo alternative splicing of 10 possible exons to generate variant isoforms. A number of CD44 variant isoforms expressed by tumor cells have been correlated with metastatic and proliferative behavior. In this study, we have characterized CD44 iso