CD44 is a glycosylated adhesion molecule which may undergo alternative splicing of 10 possible exons to generate variant isoforms. A number of CD44 variant isoforms expressed by tumor cells have been correlated with metastatic and proliferative behavior. In this study, we have characterized CD44 iso
Involvement of CD44 variant isoforms in hyaluronate adhesion by human activated T cells
β Scribed by Edi Galluzzo; Nicola Albi; Stefano Fiorucci; Carla Merigiola; Loredana Ruggeri; Antonella Tosti; Carlo E. Grossi; Andrea Velardi
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 956 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0014-2980
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## CD3' WT31-peripheral T lymphocytes lack T44 (CD28), a surface molecule involved in activation of T cells bearing the CrJP heterodimer We have applied two-color fluorescence cytofluorometric techniques to the analysis of the distribution of T44 and CD3 antigens in peripheral blood human lymphocte
## Abstract CD44 core and splice variant exon expression was investigated in the stratified transitional epithelium of the urinary tract and in normal and malignant bladder epithelial cell lines __in vitro.__ Antibodies against core CD44 epitopes and splice exon variants v3, v4/5, v5 and v6 showed