Upgrading and Downgrading of Prostate Cancer from Biopsy to Radical Prostatectomy: Incidence and Predictive Factors Using the Modified Gleason Grading System and Factoring in Tertiary Grades

Upgrading and Downgrading of Prostate Ca

✍ Jonathan I. Epstein; Zhaoyong Feng; Bruce J. Trock; Phillip M. Pierorazio 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 137 KB

## Background: Prior studies assessing the correlation of gleason score (gs) at needle biopsy and corresponding radical prostatectomy (rp) predated the use of the modified gleason scoring system and did not factor in tertiary grade patterns. ## Objective: To assess the relation of biopsy and rp g

Usefulness of the 2005 International Soc

Usefulness of the 2005 International Society of Urologic Pathology Gleason grading system in prostate biopsy and radical prostatectomy specimens

✍ Hiroji Uemura; Koji Hoshino; Takeshi Sasaki; Yasuhide Miyoshi; Hitoshi Ishiguro; 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 153 KB

1004 PREDICTION OF SIGNIFICANT DOWNGRADI

1004 PREDICTION OF SIGNIFICANT DOWNGRADING (GLEASON-SCORE ≤ 3+4) BETWEEN BIOPSY SPECIMENS AND FINAL PATHOLOGY IN A CONTEMPORARY RADICAL PROSTATECTOMY COHORT OF 321 MEN WITH BIOPSY HIGH GRADE (≥ 4+4) ProsTaTe cancer

✍ J. Hansen; H. Isbarn; F.K.H. Chun; L.A. Kluth; G. Sauter; M. Graefen; T. Steuber 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 203 KB

The ability of prostate-specific antigen

The ability of prostate-specific antigen (PSA) density to predict an upgrade in Gleason score between initial prostate biopsy and prostatectomy diminishes with increasing tumour grade due to reduced PSA secretion per unit tumour volume

✍ Niall M. Corcoran; Rowan G. Casey; Matthew K.H. Hong; John Pedersen; Stephen Con 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 183 KB

The ability of prostate-specific antigen

The ability of prostate-specific antigen (PSA) density to predict an upgrade in Gleason score between initial prostate biopsy and prostatectomy diminishes with increasing tumour grade due to reduced PSA secretion per unit tumour volume

✍ Niall M. Corcoran; Rowan G. Casey; Matthew K.H. Hong; John Pedersen; Stephen Con 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 183 KB

Study Type – Diagnostic (exploratory cohort) Level of Evidence 2b **What's known on the subject? and What does the study add?** Due to sampling error, the Gleason score of clinically localized prostate cancer is frequently underestimated at the time of initial biopsy. Given that this may lead to