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Up-regulation of transcriptional factor E2F1 in papillary and anaplastic thyroid cancers

✍ Scribed by Masamitsu Onda; Hisaki Nagai; Akira Yoshida; Shizuyo Miyamoto; Shin-ichi Asaka; Junko Akaishi; Keisuke Takatsu; Mitsuji Nagahama; Kouichi Ito; Kazuo Shimizu; Mitsuru Emi


Book ID
106251791
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
398 KB
Volume
49
Category
Article
ISSN
1435-232X

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## Abstract Phosphatidylinositol 3‐kinase (PI3K) signaling controls survival and proliferation of cancer cells and is activated in around 60% of pancreatic ductal adenocarcinomas (PDACs). Although not entirely clarified, PI3K signaling is linked to cell cycle progression of PDAC cells. In this stud