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Transcription factor FBI-1 acts as a dual regulator in adipogenesis by coordinated regulation of cyclin-A and E2F-4

โœ Scribed by Matthias Laudes; Roman Bilkovski; Frank Oberhauser; Andrea Droste; Matthias Gomolka; Uschi Leeser; Michael Udelhoven; Wilhelm Krone


Book ID
105796685
Publisher
Springer
Year
2008
Tongue
English
Weight
418 KB
Volume
86
Category
Article
ISSN
0946-2716

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Previous studies indicated that DNA adducts formed by a carcinogenic diol epoxide, 7r,8t-dihydroxy-9t, 10t-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene (BPDE), can increase the affinity of the transcription factor Sp1 for DNA sequences that are not normally specific binding sites. It was suggested that a