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Up-regulation of neural stem cell markers suggests the occurrence of dedifferentiation in regenerating spinal cord

✍ Scribed by Sally Walder; Fang Zhang; Patrizia Ferretti

Book ID: 106116001
Publisher: Springer-Verlag
Year: 2003
Tongue: English
Weight: 339 KB
Volume: 213
Category: Article
ISSN: 0949-944X
DOI: 10.1007/s00427-003-0364-2

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## Abstract Transplantation of neural stem cells (NSC) into lesioned spinal cord offers the potential to increase regeneration by replacing lost neurons or oligodendrocytes. The majority of transplanted NSC, however, typically differentiate into astrocytes that may exacerbate glial scar formation.