Transplantation of neural stem cells (NSCs) has shown promise for improving functional recovery after spinal cord injury (SCI). The inhospitable milieu of injured spinal cord, however, does not support survival of grafted NSCs, reducing therapeutic efficacy of transplantation. The present study soug
Effects of Embryonic Neural Stem Cell Transplantation on DNA Damage in the Brain and Spinal Cord Following Spinal Cord Injury
โ Scribed by T. Dagci; S. Konyalioglu; A. Keser; G. Kayalioglu
- Publisher
- Springer US
- Year
- 2009
- Tongue
- English
- Weight
- 411 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0090-2977
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๐ SIMILAR VOLUMES
## Abstract Transplantation of neural stem cells (NSC) into lesioned spinal cord offers the potential to increase regeneration by replacing lost neurons or oligodendrocytes. The majority of transplanted NSC, however, typically differentiate into astrocytes that may exacerbate glial scar formation.
## Abstract Incomplete spinal cord injury (SCI) elicits structural plasticity of the spared motor system, including the motor cortex, which may underlie some of the spontaneous recovery of motor function seen after injury. Promoting structural plasticity may become an important component of future