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Up-regulation of insulin-like growth factor axis components in human primary prostate cancer correlates with tumor grade

✍ Scribed by Yongde Liao; Ulrich Abel; Rainer Grobholz; Alexander Hermani; Lutz Trojan; Peter Angel; Doris Mayer

Book ID
116534028
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
489 KB
Volume
36
Category
Article
ISSN
1532-8392

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## Abstract The insulin‐like growth factor (IGF) axis plays a role in growth and progression of prostate cancer. High circulating IGF‐1 levels have been associated with an increased risk of prostate cancer. Results for IGF binding protein 3 (IGFBP‐3) are inconclusive. Some studies have indicated th