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Up-regulation of human β-defensin 2 by interleukin-1β in A549 cells: involvement of PI3K, PKC, p38 MAPK, JNK, and NF-κB

✍ Scribed by Byeong-Churl Jang; Ki-Jo Lim; Ji-Hye Paik; Young-Kyu Kwon; Sang-Woo Shin; Sang-Chan Kim; Tae-Young Jung; Taeg Kyu Kwon; Jae-We Cho; Won-Ki Baek; Sang-Pyo Kim; Min-Ho Suh; Seong-Il Suh

Book ID: 116288777
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 346 KB
Volume: 320
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2004.06.049

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## Abstract Interleukin‐1β (IL‐1β) has been shown to induce the expression of intercellular adhesion molecule‐1 (ICAM‐1) on airway epithelial cells and contributes to inflammatory responses. However, the mechanisms regulating ICAM‐1 expression by IL‐1β in human A549 cells was not completely underst

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