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ROLE OF P38 MAPK, AP-1, AND NF-κB IN INTERLEUKIN-1β-INDUCED IL-8 EXPRESSION IN HUMAN VASCULAR SMOOTH MUSCLE CELLS

✍ Scribed by Young D Jung; Fan Fan; David J McConkey; Marina E Jean; Wenbiao Liu; Niels Reinmuth; Oliver Stoeltzing; Syed A Ahmad; Alexander A Parikh; Naofumi Mukaida; Lee M Ellis


Book ID
118286821
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
366 KB
Volume
18
Category
Article
ISSN
1043-4666

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## Abstract Matrix metalloproteinases (MMPs) are responsible for degradation of extracellular matrix and play important roles in cell migration, proliferation, and tissue remodeling related to airway inflammation. Interleukin‐1β (IL‐1β) has been shown to induce MMP‐9 production in many cell types a