## Abstract Sphingosine 1‐phosphate (S1P) has been shown to regulate expression of several genes in vascular smooth muscle cells (VSMCs) and contributes to arteriosclerosis. However, the mechanisms regulating epidermal growth factor receptor (EGFR) expression by S1P in aortic VSMCs remain unclear.
✦ LIBER ✦
Curcumin inhibits ox-LDL-induced MCP-1 expression by suppressing the p38MAPK and NF-κB pathways in rat vascular smooth muscle cells
✍ Scribed by Yi Zhong; Tingrong Liu; Zhigang Guo
- Publisher
- SP Birkhäuser Verlag Basel
- Year
- 2011
- Tongue
- English
- Weight
- 320 KB
- Volume
- 61
- Category
- Article
- ISSN
- 1420-908X
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## Abstract The expression of matrix metalloproteinase‐9 (MMP‐9) has been implicated in progression of atherosclerotic lesions. The role and importance of the signaling pathway in the transcriptional regulation of MMP‐9 in human aortic smooth muscle cells (HASMC) was examined. Tumor necrosis factor