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Up-regulation by clarithromycin of α1-acid glycoprotein expression in liver and primary cultured hepatocytes

✍ Scribed by Takafumi Komori; Hirofumi Kai; Kazuki Shimoishi; Koki Kabu; Ayumi Nonaka; Toru Maruyama; Keiji Tamura; Masaki Otagiri

Book ID
113992804
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
462 KB
Volume
62
Category
Article
ISSN
0006-2952

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✍ Thierry Fournier; Najet Mejdoubi; Dagui Monnet; Geneviève Durand; Dominique Porq 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 582 KB

The serum level of rat a,-acid glycoprotein is significantly increased by treatment with phenobarbital, and in uiuo studies have shown that phenobarbital seems to act mainly at the transcriptional level. To show the direct mediating effect of phenobarbital on a,-acid glycoprotein gene expression, we