Regulation of multidrug resistance 2 P-glycoprotein expression by bile salts in rats and in primary cultures of rat hepatocytes
✍ Scribed by Seema Gupta; R. Todd Stravitz; William M. Pandak; Michael Müller; Z. Reno Vlahcevic; Phillip B. Hylemon
- Book ID
- 118686788
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 350 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0270-9139
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Although it has been well established that the drug efflux pump P-glycoprotein (P-gp) protects the brain against the entry of cytotoxic drugs, its real in situ localization, i.e., at brain capillary endothelial cells or on astrocyte foot processes, is still controversial. The aim of this study was t
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