Unusual α-glycosylation with galactosyl donors with a C2 ester capable of neighboring group participation
✍ Scribed by Langqiu Chen; Fanzuo Kong
- Book ID
- 104253462
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- French
- Weight
- 334 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
Predominant or even pure (13)-a-linked products can be generated in glycosylation with glucosyl trichloroacetimidate donors with a C2 ester capable of neighboring group participation. Benzoylation of either the donors or acceptors gave more b-linkage, while 4,6-O-benzylidenation of the acceptor gave
Predominant a-linked products can be generated in glycosylation involving galactosyl trichloroacetimidate donors with 2-naphthylmethyl (NAP) as the non-participating group at C-2 position. The above-mentioned donor was successfully utilized for the synthesis of a-galactosyl ceramide.