Unusual α-Glycosylation with Galactosyl Donors with a C2 Ester Capable of Neighboring Group Participation.
✍ Scribed by Langqiu Chen; Fanzuo Kong
- Book ID
- 101946019
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 169 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
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📜 SIMILAR VOLUMES
Predominant or even pure (13)-a-linked products can be generated in glycosylation with glucosyl trichloroacetimidate donors with a C2 ester capable of neighboring group participation. Benzoylation of either the donors or acceptors gave more b-linkage, while 4,6-O-benzylidenation of the acceptor gave
Predominant a-linked products can be generated in glycosylation involving galactosyl trichloroacetimidate donors with 2-naphthylmethyl (NAP) as the non-participating group at C-2 position. The above-mentioned donor was successfully utilized for the synthesis of a-galactosyl ceramide.