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Unusual ‘Spike-wave stupor’ in a patient with manic-depressive psychosis treated with amitriptyline

✍ Scribed by E. Rumpl; H. Hinterhuber

Publisher: Springer
Year: 1981
Tongue: English
Weight: 279 KB
Volume: 226
Category: Article
ISSN: 0340-5354
DOI: 10.1007/bf00313441

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✦ Synopsis

'Spike-wave stupor' was observed in a 58-year-old male patient with manic-depressive psychosis. Almost continuous atypical spike-wave activity was seen in conjunction with a stuporous episode with stereotyped automatism. Intravenous diazepam ended both the electroencephalographic epileptiform discharges and the clinical stupor. Before and during this episode the patient was treated with an average-dose amitriptyline monotherapy. There was no family history of epileptic seizures. The patient had had electroconvulsive therapy. The history suggests that the analeptic property of amitriptyline induced the 'spike-wave stupor' in this patient.

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