Prolonged residual catatonia or prolonged neuroleptic-induced Parkinsonism following catatonic stupor in a patient with manic–depressive illness
✍ Scribed by Kazumasa Suzuki; Takehisa Takano; Kae Ito; Yukio Ebina; Hiroo Matsuoka; Shuichi Awata
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 42 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0885-3185
No coin nor oath required. For personal study only.
✦ Synopsis
which was roughly four times the entire country's total number of PD patients at the time. Consequently, we believe that these particular neurodegenerative conditions co-occur far more frequently than could be expected by chance alone and/or reflect common etiology, pathogenic process, or common vulnerabilities between specific neuronal populations. We also believe that the cases described by Klos and colleagues, 1 with comparative short duration of illness (4 and 1.5 years), demonstrated such short survival because of much more severe motor neuron dysfunction than were seen in our series. In our series of 14 patients, including patients we found after 1995, Parkinsonism long predated motor neuron dysfunction: symptomatic Parkinsonism duration ranged from 5 to 26 years compared with Ͻ 1 to 11 years of motor neuron dysfunction. Finally, Klos and colleagues 1 made no mention of family history of neurodegeneration. We observed that 5 of 14 patients had a close relative with AD, which may also contribute to eventual clinicopathological outcomes.