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Unusual specificity of polyethylene glycol-modified thermolysin in peptide synthesis catalyzed in organic solvents

โœ Scribed by Anne Ferjancic; Antoine Puigserver; Hubert Gaertner

Publisher
Springer Netherlands
Year
1988
Tongue
English
Weight
309 KB
Volume
10
Category
Article
ISSN
0141-5492

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Peptide synthesis catalyzed by polyethyl
Peptide synthesis catalyzed by polyethylene glycol-modified chymotrypsin in organic solvents
โœ Hubert F. Gaertner; Antoine J. Puigserver ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 795 KB

Chymotrypsin modified with polyethylene glycol was successfully used for peptide synthesis in organic solvents. The benzene-soluble modified enzyme readily catalyzed both aminolysis of N-benzoyl-L-tyrosine p-nitroanilide and synthesis of N-benzoyl-L-tyrosine butylamide in the presence of trace amoun