## Abstract For Abstract see ChemInform Abstract in Full Text.
Unusual amino acids VII. Asymmetric synthesis of 3- and 4- pyridylalanines
✍ Scribed by Christian Döbler; H.-J. Kreuzfeld; M. Michalik; H.W. Krause
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 332 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0957-4166
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract For Abstract see ChemInform Abstract in Full Text.
All the four individual isomers of R-methylphenylalanine have been synthesized in very high optical purities by utilizing in part the chiral imide enolate bromination methodology of Evans and co-workers. Substitution of the diastereotopic X-hydrogens of many a-amino acids provides inprinciple, an a
The synthesis of all four individual isomers of 3-methyl-3-(2'-naphthyl)analine was accomplished using asymmetric conjugate 1 A-addition followed by direct or indirect azidation using an Evans-type chiral auxiliary (4-phenyl-2-oxazolidinone).