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Asymmetric synthesis of unusual amino acid: Synthesis of four isomers of β-methyl-3-(2′-naphthyl)alanine

✍ Scribed by Wei Yuan; Victor J. Hruby

Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
173 KB
Volume
38
Category
Article
ISSN
0040-4039

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✦ Synopsis

The synthesis of all four individual isomers of 3-methyl-3-(2'-naphthyl)analine was accomplished using asymmetric conjugate 1 A-addition followed by direct or indirect azidation using an Evans-type chiral auxiliary (4-phenyl-2-oxazolidinone).

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