The composition of an amino acid solution for intravenous use in newborns is discussed in the light of the metabolic kinetics of its constituents. Such a solution would be optimal when based on the transfer characteristics of the single amino acids used. Under these circumstances one would avoid imb
Untersuchungen über die Verwertung parenteral zugeführter Aminosäuren bei Frühgeborenen und hypotrophen Neugeborenen
✍ Scribed by U. Bürger; H. Wolf
- Publisher
- Springer
- Year
- 1976
- Tongue
- English
- Weight
- 464 KB
- Volume
- 123
- Category
- Article
- ISSN
- 0340-6997
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✦ Synopsis
An amino acid solution composed according to pharmacokinetic criteria was infused in 12 premature and 4 full-term infants. Imbalances of amino acids were not observed when the upper limit of the fasting level was accepted as a measure for balance or imbalance. The net transfer of total amino acids increased by about 40% over that in former experiments (second communication (4)). A decrease of cystine, a semiessential amino acid, could be avoided. The results were compared with the literature. During infusion, the urinary excretion of amino acids was not increased showing nearly complete utilization of the infused amin acids.
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