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Untangling Ligand Induced Activation and Desensitization of G-Protein–Coupled Receptors

✍ Scribed by Woolf, Peter J.; Linderman, Jennifer J.


Book ID
118515572
Publisher
Biophysical Society
Year
2003
Tongue
English
Weight
292 KB
Volume
84
Category
Article
ISSN
0006-3495

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Modeling Activation and Desensitization
✍ TODD A RICCOBENE; GENEVA M OMANN; JENNIFER J LINDERMAN 📂 Article 📅 1999 🏛 Elsevier Science 🌐 English ⚖ 425 KB

Signaling through G-protein coupled receptors is one of the most prevalent and important methods of transmitting information to the inside of cells. Many mathematical models have been proposed to describe this type of signal transduction, and the ternary complex (ligand/receptor/G-protein) model and