Unstable ring Y chromosome in an aspermic male
โ Scribed by P. Steinbach; H. Fabry; W. Scholz
- Publisher
- Springer
- Year
- 1979
- Tongue
- English
- Weight
- 295 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0340-6717
No coin nor oath required. For personal study only.
โฆ Synopsis
A ring Y chromosome was found in a male showing growth retardation and aspermia but normally developed external genitalia. The ring does not display either the characteristic brilliant Y fluorescence or the typical late-replicating heterochromatin.
๐ SIMILAR VOLUMES
An infertile male carrying an unbalanced Y/13 translocation is described. Meiotic studies suggest that the unbalanced translocation does not affect meiotic division. An individual with the karyotype 46,XY, der(13),t(Y;13)(q12;pll) was found during a cytogenetic survey of male subfertile patients. T
Investigations by fluorescence in situ hybridization and a Y-specific probe (Y190) of a male patient with a Y ring chromosome, 46,X,r(Y) showed four bright fluorescent spots within the ring. Thus, using this technique, it is possible to suggest that the ring originates from the duplication of the sh
In the mouse XYY males are sterile, presumably because pairing abnormalities resulting from the presence of three sex chromosomes lead to meiotic breakdown. We have produced male mice, designated XYY\*X, that have three sex chromosomes pairing regions but only one intact Y chromosome. Unexpectedly X