Meiotic chromosomes in an infertile male with an unbalanced Y/13 translocation

✍ Scribed by Diana J. Curtis

• Publisher: Springer
• Year: 1977
• Tongue: English
• Weight: 313 KB
• Volume: 37
• Category: Article
• ISSN: 0340-6717
• DOI: 10.1007/bf00393605

✦ Synopsis

An infertile male carrying an unbalanced Y/13 translocation is described. Meiotic studies suggest that the unbalanced translocation does not affect meiotic division.

An individual with the karyotype 46,XY, der(13),t(Y;13)(q12;pll) was found during a cytogenetic survey of male subfertile patients. The mitotic and meiotic chromosome complements of this patient are described together with testicular histology, spermiogram, hormone levels and clinical history.

Clinical Description

The patient, aged 26 years, has been involuntarily infertile for 4 years. He is 6 ft 1 ins tall with normal male physique, normal sexual organs, normal sexuality and there is no history of previous testicular trauma or disease. Urinary and plasma FSH and LH levels are within normal limits. The patient's family were not available for chromosome studies. The patient has one sister who is fertile and there is no history of infertility in his parents' generation.