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Unstable, non-mutational expression of resistance to the thymidine analogue, trifluorothymidine in CHO cells

✍ Scribed by Gerald M. Adair; June H. Carver


Book ID
113191684
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
394 KB
Volume
60
Category
Article
ISSN
0027-5107

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Thymidine analogue reverse transcriptase
✍ Anne-GeneviΓ¨ve Marcelin; Constance Delaugerre; Marc Wirden; Pedro Viegas; Anne S πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 71 KB

During ZDV or d4T exposure, mutations at codons 41, 67, 70, 210, 215, and 219 can be selected and were named thymidine analogue mutations (TAMs). Some previous results suggested that different TAMs patterns could exist and that the kind of TAMs pattern could influence the virological response to som