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Unstable Expression of the Multi-Drug-Resistant Phenotype in Chinese Hamster Ovary Cells Resistant to Okadaic Acid

โœ Scribed by Hiroko Tohda; Masashi Takao; Akihiko Kikuchi; Takeshi Yasumoto; Akira Yasui

Book ID
115579964
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
284 KB
Volume
232
Category
Article
ISSN
0006-291X

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We have observed quantitative and qualitative differences in the mutability and mutagen-specificity of various drug-resistance marker loci in Chinese hamster ovary (CHO) cells, which suggest that mammalian gene loci may differ in their relative mutability by a given mutagenic agent. We have used the