𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Unstable and Thalassemic α Chain Hemoglobin Variants: A Cause of Hb H Disease and Thalassemia Intermedia

✍ Scribed by Wajcman, Henri; Traeger-Synodinos, Jan; Papassotiriou, Ioannis; Giordano, Piero C.; Harteveld, Cornelis L.; Baudin-Creuza, Véronique; Old, John

Book ID
125844488
Publisher
Informa plc
Year
2008
Tongue
English
Weight
527 KB
Volume
32
Category
Article
ISSN
0363-0269

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Association of unstable hemoglobin varia
Association of unstable hemoglobin variants and heterozygous ?-thalassemia: Example of a new variant Hb acharnes or [?53(D4) Ala ? Thr]
✍ Papassotiriou, I.; Traeger-Synodinos, J.; Prom�, D.; Kister, J.; Stamou, E.; Lia 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 112 KB

We report here the functional and structural characterization of Hb Acharnes [␤53(D4) Ala → Thr], an unstable and electrophoretically silent variant, that was found associated in trans with a ␤ 0 -thalassemic mutation (IVSI-1 G → A), in a patient with thalassemia intermedia syndrome. This case is di

Hb Q-Thailand-Hb H disease in a chinese
Hb Q-Thailand-Hb H disease in a chinese living in Geneva, Switzerland: Characterization of the variant and identification of the two α-thalassemic chromosomes
✍ P. Beris; P. Huber; P. A. Miescher; J. B. Wilson; A. Kutlar; S. S. Chen; Dr. T. 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 English ⚖ 402 KB 👁 2 views

Data on a 24-year-old Chinese male with Hb Q-Thailand-Hb H disease are presented. The hemoglobin variant was characterized by fast microprocedures, mainly by reverse-phase high-performance liquid chromatography. Gene mapping analyses identified the a-thalassemia-2, which is associated with the a-Q c