Unscheduled DNA synthesis: Some statistical thoughts

✍ Scribed by Ajit K. Thakur

• Book ID: 104625308
• Publisher: Springer
• Year: 1987
• Tongue: English
• Weight: 889 KB
• Volume: 3
• Category: Article
• ISSN: 0742-2091
• DOI: 10.1007/bf00058455

✦ Synopsis

Statistical interpretation of results of experiments involving unscheduled DNA synthesis is examined from a design standpoint. Most appropriate methods currently in use are evaluated and some modifications and extensions are suggested. Concerns about replication and~or interaction errors are evaluated and methods for their appropriate handling are discussed. It is suggested that methods incorporating both dose-response and heterogeneity statistics shouM be considered in treating results from unscheduled DNA synthesis experiments. Proper designs for such experiments are emphasized.