✦ LIBER ✦

Unsaturated thioacetic acids as novel mechanism-based inhibitors of peptidylglycine α-hydroxylating monooxygenase

✍ Scribed by P. Casara; A. Ganzhorn; C. Philippo; M-C. Chanal; C. Danzin

Book ID: 108038977
Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 232 KB
Volume: 6
Category: Article
ISSN: 0960-894X
DOI: 10.1016/0960-894x(96)00041-8

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Probing the Peptidylglycine α-Hydroxylat

Probing the Peptidylglycine α-Hydroxylating Monooxygenase Active Site with Novel 4-Phenyl-3-butenoic Acid Based Inhibitors

✍ Emma Langella; Sébastien Pierre; Wadih Ghattas; Michel Giorgi; Marius Réglier; M 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 838 KB

Specific inhibition of the copper-containing peptidylglycine alpha-hydroxylating monooxygenase (PHM), which catalyzes the post-translational modification of peptides involved in carcinogenesis and tumor progression, constitutes a new approach for combating cancer. We carried out a structure-activity

Selective mechanism-based inactivation o

Selective mechanism-based inactivation of peptidylglycine α-hydroxylating monooxygenase in serum and heart atrium vs. brain

✍ Frank N. Bolkenius; Axel J. Ganzhorn; Marie-Christine Chanal; Charles Danzin 📂 Article 📅 1997 🏛 Elsevier Science 🌐 English ⚖ 922 KB

A new proposal for the mechanism of glyc

A new proposal for the mechanism of glycine hydroxylation as catalyzed by peptidylglycine α-hydroxylating monooxygenase (PHM)

✍ Terence C Owen; David J Merkler 📂 Article 📅 2004 🏛 Elsevier Science 🌐 English ⚖ 227 KB

Peptidylglycine-α-Hydroxylating Monooxyg

Peptidylglycine-α-Hydroxylating Monooxygenase Generates Two Hydroxylated Products from Its Mechanism-Based Suicide Substrate, 4-Phenyl-3-butenoic Acid †

✍ Driscoll, William J.; König, Simone; Fales, Henry M.; Pannell, Lewis K.; Eipper, 📂 Article 📅 2000 🏛 American Chemical Society 🌐 English ⚖ 119 KB

Catalytic enantioselective synthesis of

Catalytic enantioselective synthesis of optically active α-hydroxyl-β,γ-unsaturated acid esters as novel side chains of cerebrosides

✍ Wang, Lei; Liu, Ruiquan; Lv, Cong; Ou, Junjun; Liu, Feng; Liu, Shangzhong; Wang, 📂 Article 📅 2013 🏛 Elsevier Science 🌐 English ⚖ 318 KB

Design and Synthesis of Pyrrolidine-5,5-

Design and Synthesis of Pyrrolidine-5,5- trans- lactams (5-Oxo-hexahydro-pyrrolo[3,2- b ]pyrroles) as Novel Mechanism-Based Inhibitors of Human Cytomegalovirus Protease. 1. The α-Methyl- trans -lactam Template

✍ Borthwick, Alan D.; Angier, S. Jane; Crame, Andrew J.; Exall, Anne M.; Haley, Te 📂 Article 📅 2000 🏛 American Chemical Society 🌐 English ⚖ 183 KB